← Blog

Effective Urticaria Treatment: Antihistamines, Oral Corticosteroids, and Managing Triggering Factors

A middle-aged Hispanic woman sitting on a medical examination table attentively listens to a Hispanic doctor holding a clipboard. On the table, there are boxes of medications labeled 'H1 Antihistamines.' In the background, a poster displays common triggering factors of urticaria, highlighting treatment options such as oral corticosteroids and omalizumab.

Urticaria is a common skin condition characterized by the appearance of itchy welts and, in some cases, angioedema. Although it is often self-limiting, urticaria can be chronic and significantly impact patients' quality of life. The treatment of urticaria focuses on the use of H1 antihistamines and the management of triggering factors that may exacerbate the condition.

Diving Deeper into Urticaria Treatment

The management of both acute and chronic urticaria begins with the identification and avoidance of known triggering factors. These may include medications, foods, infections, and physical stimuli such as cold or pressure. In cases of chronic inducible urticaria, it is crucial to conduct provocation tests to identify specific triggers.

Second-generation H1 antihistamines are the cornerstone of pharmacological treatment due to their efficacy and safety profile. In situations where the response to standard treatment is insufficient, increasing the dose up to four times the recommended amount may be considered. In refractory cases, the use of omalizumab has proven effective, especially in chronic spontaneous urticaria.

In cases of acute exacerbation, oral corticosteroids may be used short-term to control symptoms. However, prolonged use is not recommended due to potential side effects. Patient education on avoiding triggers and the proper use of medications is essential for the successful management of urticaria.

Conclusions

The treatment of urticaria requires a comprehensive approach that combines pharmacotherapy with the identification and management of triggering factors. Second-generation H1 antihistamines are the first-line treatment, with additional options such as omalizumab for more severe cases. Personalizing treatment based on individual patient characteristics and treatment response is key to improving the quality of life for patients with urticaria.

Referencias


Created 6/1/2025