Managing Menopause: Hormone Replacement Therapy and Alternative Treatments for Climacteric Symptoms in Women's Health

The menopause is a crucial stage in a woman's life that marks the end of reproductive capacity. This natural process can be accompanied by a series of climacteric symptoms that affect quality of life, such as hot flashes, night sweats, and mood changes. Hormone replacement therapy (HRT) has long been the standard treatment for alleviating these symptoms, but concerns about its risks have led to a growing interest in alternative treatments.

Diving Deeper into Menopause Management

Hormone replacement therapy remains the most effective treatment for vasomotor symptoms, such as hot flashes, and is also recommended for the prevention of osteoporosis in postmenopausal women at low to moderate fracture risk. However, it is crucial to individualize treatment to maximize benefits and minimize risks, considering factors such as the type, dosage, and duration of HRT (see more).

On the other hand, alternative treatments have gained popularity, especially among women seeking non-hormonal options. These include the use of non-hormonal medications such as selective serotonin reuptake inhibitors (SSRIs) and cognitive-behavioral therapy, which have proven effective for managing vasomotor symptoms (see more). Additionally, the use of botanical products and supplements, while less effective than HRT, remains an option for many women, although evidence regarding their efficacy and safety is limited.

Conclusions

Managing menopause requires a comprehensive approach that considers both hormone replacement therapy and alternative treatments. It is essential for physicians to individually assess each patient, considering their risks and personal preferences, to provide treatment that enhances their quality of life. Continuous education and staying updated on the latest evidence are fundamental to providing optimal care for women during this transitional stage.

References

• [1] Management of postmenopausal women: Collège National des Gynécologues et Obstétriciens Français (CNGOF) and Groupe d'Etude sur la Ménopause et le Vieillissement (GEMVi) Clinical Practice Guidelines.
• [2] Evidence-based approaches for the management of side-effects of adjuvant endocrine therapy in patients with breast cancer.
• [3] Complementary and Alternative Approaches to Menopause.
• [4] Non-oestrogen-based and complementary therapies for menopause.

Created 13/1/2025