Influenza Treatment: Clinical Management, Antiviral Drugs, and Prophylaxis Strategies for Doctors

Influenza, a highly contagious respiratory illness, continues to pose a significant challenge to public health worldwide. Despite advancements in vaccination, the variability of viral strains and insufficient vaccination coverage complicate effective prevention. In this context, influenza treatment focuses on clinical management, the use of antiviral drugs, and influenza prophylaxis strategies to mitigate associated complications.
The clinical management of influenza includes appropriate care and rest, along with the administration of antiviral drugs when necessary. Neuraminidase inhibitors and polymerase inhibitors are the most commonly used classes of antiviral drugs. These medications are most effective when administered within the first 48 hours of symptom onset, reducing the duration of illness and the severity of symptoms. However, resistance to these drugs has been documented, underscoring the need for the development of new antiviral options.
In vulnerable populations, such as geriatric patients, the treatment and prevention of influenza require a more careful approach. Antivirals like oseltamivir have proven effective in reducing mortality and complications in these groups. Additionally, vaccination remains a crucial strategy for prevention, especially in children and older adults, who are more susceptible to influenza complications.
Influenza prophylaxis through annual vaccination is the cornerstone of prevention. Vaccination not only protects the individual but also reduces community transmission of the virus. In situations of high exposure, such as travel or mass gatherings, vaccination is strongly recommended, and in some cases, the use of antiviral drugs as a preventive measure is advised.
In conclusion, managing influenza requires a multifaceted approach that combines vaccination, strategic use of antiviral drugs, and community prevention measures. Ongoing research and the development of new antiviral drugs are essential to address current limitations and improve clinical outcomes in future influenza seasons.
Referencias
- [1] Influenza antivirals and their role in pandemic preparedness.
- [2] Antiviral Approaches against Influenza Virus.
- [3] Treatment and prevention of influenza in geriatric patients.
- [4] Recommendations for Prevention and Control of Influenza in Children, 2022-2023.
- [5] Influenza.
Created 2/1/2025