Gastric Cancer Treatment: Partial or Total Gastrectomy, Adjuvant Chemotherapy, and Nutritional Support

The treatment of gastric cancer presents a significant medical challenge that necessitates a multidisciplinary approach. Partial or total gastrectomy is a commonly employed surgical intervention, often complemented by adjuvant chemotherapy and a rigorous focus on nutritional support. This article delves into current strategies for managing gastric cancer, emphasizing the critical role of clinical nutrition in the perioperative context.

Profundizando en el Tratamiento

Total gastrectomy is a surgical procedure that, while effective, is associated with significant weight loss and decreased caloric intake. A recent study evaluated the impact of immunonutrition based on eicosapentaenoic acid in patients undergoing total gastrectomy. The results indicated that, although supplementation did not significantly reduce postoperative weight loss, clinical nutrition remains a crucial component of perioperative management.

Conversely, post-gastrectomy malnutrition has been identified as a factor negatively affecting long-term survival. The assessment of the Nutritional Risk Index (NRI) before and after surgery has demonstrated that malnutrition is associated with poorer overall survival. This finding underscores the necessity for effective nutritional interventions to enhance postoperative outcomes.

Conclusiones

The treatment of gastric cancer through gastrectomy and adjuvant chemotherapy is complex and requires a comprehensive approach that includes adequate nutritional support. Evidence suggests that attention to clinical nutrition can significantly influence recovery and long-term survival of patients. It is essential for medical teams to consider the implementation of personalized nutritional strategies to optimize treatment outcomes.

Referencias

• [1] Randomized clinical trial comparing standard diet with perioperative oral immunonutrition in total gastrectomy for gastric cancer.
• [2] Impact of Malnutrition After Gastrectomy for Gastric Cancer on Long-Term Survival.

Created 6/1/2025