Breast Cancer Treatment: Mastectomy, Lumpectomy, Adjuvant Chemotherapy, and HER2 Targeted Therapies

The breast cancer treatment landscape has evolved significantly over the past few decades, offering patients a variety of therapeutic options tailored to the specific characteristics of their disease. In this context, surgery, adjuvant chemotherapy, and targeted therapies play a crucial role in managing this pathology. This article reviews recent advances in these areas, providing a comprehensive overview for healthcare professionals.

Diving Deeper into Breast Cancer Treatment

Surgery remains a cornerstone in the treatment of breast cancer, with options ranging from mastectomy to lumpectomy, depending on the stage and characteristics of the tumor. The evolution of surgical techniques has allowed for greater preservation of breast tissue, improving the quality of life for patients [1].

Adjuvant chemotherapy is utilized to reduce the risk of recurrence, especially in high-risk patients. The choice of chemotherapy regimen is based on factors such as cancer subtype and response to previous treatments [2]. In the case of HER2-positive breast cancer, the incorporation of targeted therapies like trastuzumab has significantly improved outcomes [3].

Targeted therapies have revolutionized breast cancer treatment, allowing for a more personalized approach. These therapies focus on specific molecular targets, such as the HER2 receptor, and have proven effective in improving survival and reducing disease progression [4]. Additionally, research in hormone therapy continues to advance, offering new options for patients with hormone-dependent tumors [5].

Conclusions

The treatment of breast cancer is a constantly evolving field, with significant advances in surgery, chemotherapy, and targeted therapies. The personalization of treatment, based on the molecular characteristics of the tumor, has improved clinical outcomes and the quality of life for patients. It is essential for healthcare professionals to stay updated on these developments to provide the best possible care for their patients.

Referencias

• [1] Axillary surgery in breast cancer: An updated historical perspective.
• [2] Adjuvant and neoadjuvant therapy for breast cancer.
• [3] Neoadjuvant and adjuvant treatment of patients with HER2-positive early breast cancer.
• [4] New and Emerging Targeted Therapies for Advanced Breast Cancer.
• [5] Current trends in the treatment of HR+/HER2+ breast cancer.

Created 4/1/2025